After the Spring Festival, the climate gradually turns warmer and everything revives in the spring, which is also a period of high incidence of infectious diseases. Hepatitis A and hepatitis E are the most common infectious diseases of the digestive tract in spring, and they have many similarities, both of them are transmitted by fecal-oral route, and the transmission route is an acute infectious disease mainly by intestinal transmission, i.e., it is possible to be infected by eating food contaminated with virus or using tableware contaminated with virus. In our country, children under 10 years old, especially preschool children are more likely to be infected with hepatitis A virus, after infection with hepatitis A virus, whether or not the onset of the disease can produce a special long immunity, therefore, adults occur less hepatitis A, mainly because they may have been infected with hepatitis A virus in childhood, thus gaining immunity to hepatitis A, and there is also a special hepatitis A vaccine to prevent hepatitis A infection, but the elderly once infected with hepatitis A However, once infected with the hepatitis A virus, the elderly often develop severe hepatitis and have more complications. In contrast, the incidence of hepatitis E is relatively high and the complications are relatively numerous, which should be noted. The clinical manifestations of hepatitis A and E are similar. Patients often have fever, malaise, loss of appetite, nausea, vomiting and other gastrointestinal symptoms, and the symptoms are not typical at the beginning of the disease and are often misdiagnosed as “cold”. The diagnosis of the disease can be made by blood tests for IgM antibodies against hepatitis A and E. Patients with hepatitis A and E can get better in a month or so without turning into chronic hepatitis as long as they are treated in a timely, reasonable and standardized manner, but it is important to note that individual patients with heavy disease and no timely treatment after the onset of the disease may develop into acute liver failure, which may be life-threatening. Hepatitis A and E are both infectious diseases of the gastrointestinal tract. According to the general rule of transmission of infectious diseases, the prevention of hepatitis A and E can be avoided by paying attention to the following aspects: 1. Early detection and early isolation of the source of infection. The main sources of infection for hepatitis A and E are patients and subclinically infected persons in the incubation and early acute stages, who excrete hepatitis A or E virus from the feces, contaminate water, food and the surrounding environment, and then ingest the virus through the mouth and spread it. Therefore, confirmed or suspected patients should be promptly reported to the health epidemic prevention department for timely isolation and disinfection, and the isolation period should be no less than 3 weeks from the date of occurrence, and suspected and close contacts should be placed under medical observation within 6 weeks of contact with the patient. Hepatitis A and E patients are highly contagious before their symptoms become apparent, so they should be detected and isolated early to reduce the risk of infection and avoid a large-scale epidemic. 2.Cut off the transmission route. Prevention of hepatitis A and E is through the fecal-oral route of transmission of infectious diseases of the digestive tract, so the most important thing is to do a good job of personal hygiene and good eating habits. ① must keep the “disease from the mouth” off, pay attention to dietary hygiene, do not drink raw water, raw vegetables and fruits to wash, do not eat unclean food, especially not raw shellfish, do not eat half-cooked lamb skewers and other food, try to avoid eating in unhygienic stalls. ② usually develop good hygiene habits, good personal hygiene, wash hands before and after meals, eating utensils, tea utensils and household utensils should be frequently disinfected. ③Promote the use of public chopsticks, public spoons when dining together, it is best to implement the system of sharing meals. ④ Collective canteens in factories, schools, kindergartens, homes for the elderly, construction sites and other units should strengthen their hygiene management, and tools and containers for processing cold and hot dishes should be separated and disinfected regularly. 3.Improve your own immunity. Those who have not been infected with hepatitis A and E virus are susceptible. Immunoprophylaxis is mainly divided into two aspects, one is the active prevention by receiving vaccines. The second is passive prevention through gammaglobulin injection. For those who are negative for hepatitis A IgG antibodies can be vaccinated with hepatitis A vaccine for active prevention, and if they have been in close contact with hepatitis A patients recently, they can be vaccinated with gammaglobulin for passive immunization, the earlier the better. The immunization period is 2~3 months. At present, the hepatitis E vaccine was just released last year and has not yet been used in a large scale clinical application, and gammaglobulin is also effective in preventing hepatitis E. Therefore, the prevention of hepatitis E still focuses on strengthening dietary hygiene and preventing and entering from the mouth.