Leukopenia in peripheral blood is mainly caused by neutropenia. The main manifestations of this disease are generalized weakness and fatigue. There are many causes of leukopenia, such as: 1, decreased leukocyte production, commonly due to vitamin (especially B vitamins) deficiency, low bone marrow hematopoiesis, etc.; 2, destruction of drugs leading to leukopenia, such as anti-tumor drugs, immunosuppressants, antibiotics such as chloramphenicol, sulfonamides, etc.; 3, the destructive effect of chemical toxins such as benzene and its derivatives on peripheral blood and bone marrow leukocytes; 4, radioactive 4. radiation damage, such as radiation from various rays; 5. inhibition of bone marrow and destruction of leukocytes by certain infectious factors (such as typhoid fever) and certain bacterial endotoxins. In addition, leukopenia can be secondary to other diseases, such as hypersplenism leading to excessive destruction and autoimmune diseases leading to increased destruction of leukocytes due to increased autoantibodies. It can also be caused by immune disorders and various infections that lead to excessive consumption. Another cause is due to abnormal leukocyte distribution (normal total leukocyte count but low distribution in the blood), which is also called pseudoleukopenia, which means that there are fewer leukocytes in the circulation (because we test for leukocytes in the peripheral circulation) and there may be a lot of leukocytes adhering to the walls of the blood vessels in the microcirculation in several areas, such as the liver and spleen, which can be tested with a leukocyte release test ( This can be done by performing a leukocyte release test (subcutaneous injection of epinephrine or use of hormones, etc.) The leukocytes can rise significantly above normal, but these tests must be performed at a hospital under the supervision of a doctor. I don’t know if you have any of these conditions. The key to the treatment of leukopenia is to remove the cause, and for leukopenia and granulocytopenia of unknown cause, one or two leukocyte-raising drugs such as reserpine, shark liver alcohol, B vitamins (such as B complex, or B4, B6, etc.), inosine, gum, etc. can be taken orally. For severe leukopenia, especially granulocyte deficiency, infection prevention and treatment with biological factors such as granulocyte colony-stimulating factor should be given.