The itchy hands and feet become more and more itchy when scratched. The first consideration is insect bites or irritation of the intradermal peripheral nerves due to a dry environment. The second consideration is contact dermatitis caused by contact with certain substances, but also may be hands and feet fungal infection resulting in ringworm and tinea pedis, or sweat blisters resulting in skin inflammation, or even complications of other diseases may also lead to itching of the hands and feet, and the more you scratch the more itchy: 1. Contact dermatitis: due to local contact with exogenous substances, which leads to allergy at the contact site, and accompanied by a pronounced itching, burning or stinging sensation, which may be accompanied by lesions such as erythema and papules; 2. Tinea capitis: Tinea capitis and Tinea pedis are fungal skin diseases that occur in the palms and plantar areas of the skin. The acute damage is papules, papules, and blisters, and tinea pedis often appears as maceration, vesicles, or clusters of blisters that can be accompanied by significant itching or burning, stinging sensations, which often suggest secondary infection at this time; 3. Herpes perspicans: It is a blistering disease of the palms, feet, and plantars with small blisters deep in the epidermis that occur scattered or in clusters on the palms, sides of the fingers, or soles of the feet. The onset of the disease is mostly related to personal constitution, autonomic dysfunction, mental factors or allergic constitution, and may be accompanied by hyperhidrosis, intense itching, tingling or burning sensation; 4. neurodermatitis: the cause of the disease is still unclear, and may be related to mental factors, chronic friction, etc. It can manifest as intense itching, the more you scratch, the more itchy, especially at night. In addition, such as hyperthyroidism, diabetes, cirrhosis of the liver, kidney failure, etc., and some blood diseases, such as anemia, can also cause itching of the hands and feet, which usually cannot be relieved by scratching. It is recommended to visit a hospital promptly and actively treat the primary disease, thus relieving the symptoms of itchy hands and feet.