I. Berlin syndrome alias: ① sudden eye muscle paralysis syndrome; ② orbital pseudotumor syndrome. Summary: The syndrome is usually seen in males, with a gradual onset of involvement in one or both eyes. It has similarities with proptosis goiter, but the age of onset is later, and proptosis can occur several months before other symptoms. Etiology: The cause is unknown and may be due to titular infection, which can occur in people with hyperthyroidism or without the disease. The pathology sees inflammatory changes in the ocular muscles. Ocular features: 1. Eye pain, protrusion of the eyeball, and paralysis of the eye muscles. However, visual acuity is generally unaffected. There is no sensory impairment in the ophthalmic branch of the trigeminal nerve. 2. Eyelid edema and bulbar conjunctival edema. 3. Cephalometric X-ray, angiography, CT scan help to diagnose. V. Systemic features: no special manifestations. VI. Treatment: Anti-inflammatory and adrenal corticosteroids are effective, while preventing the occurrence of exposure keratitis.