Breast cancer targeted therapy cannot indicate advanced stage. In other malignant tumors, targeted therapy is mostly used for intermediate and advanced malignant tumors, but not in breast cancer, because the target of breast cancer targeted therapy is different, it targets human epidermal growth factor receptor-2, and if human epidermal growth factor receptor-2 shows positive, it can be treated with targeted therapy. There are two types of targeted therapy, one is monotherapy, that is, trastuzumab combined with chemotherapy, and the other is dual target therapy, that is, trastuzumab combined with patuximab and chemotherapy, so targeted therapy for breast cancer has nothing to do with middle and late stage, it is not a way of manifestation of late stage of cancer, and it is not a way of treatment for late stage of cancer.