The causes of pain in lipoma include local compression of tumor, compression of nerves by lipoma, obstruction of subcutaneous lipoma and so on. 1. Local compression of tumor: tumor cells usually grow in a swollen manner, and the enlarged tumor will not only compress the surrounding nerve tissues, but also pull the peritoneum, thus resulting in swelling and pain. 2. Lipoma invades nerves: when the tumor body of lipoma increases in size, it will involve the adjacent blood vessels and nerves, resulting in local pain, such as when the cancer invades the ribs or intercostal nerves, it will stimulate the nerves, and obvious pain symptoms will appear. 3. Obstruction of subcutaneous lipoma: for example, when subcutaneous lipoma obstructs lymphatic vessels in the organism, resulting in obstruction of blood return, which may induce pain symptoms. If the tumor is small, the pain symptoms are not very obvious. However, when the obstruction of the subcutaneous lipoma is more severe, the pain will continue to worsen. In order to avoid the growth and increase of lipoma, you should pay attention to your diet, not only avoiding alcoholic beverages, but also avoiding overly oily food. In case of lipoma with pain, it is recommended to go to regular hospital for comprehensive examination and treatment.