In the early stage of tuberculosis, when the course of the disease is within 3 months, it is easy to achieve a cure with combined anti-tuberculosis drug therapy if the diagnosis is clear. In particular, the combination of isoniazid, rifampin, ethambutol and pyrazinamide can be used continuously for 6-9 months, depending on the severity of the disease, and is completely curable for the first time. Some patients may experience adverse reactions when taking the drugs, such as nausea, vomiting, or even pain in muscles and joints, and side effects such as elevated uric acid. In the early stage, the drug can be used for a period of time, depending on the patient’s tolerance of the side effects of the drug, and if it appears intolerable the treatment plan can be adjusted at any time and does not affect the course of treatment.