With the popular application of high-resolution CT and the emphasis on health checkups by social groups, the detection and diagnosis rate of pulmonary nodules (pulmonary GGO) has increased significantly compared to a decade ago, while the corresponding qualitative diagnosis methods of pulmonary nodules have not been clearly improved, and most of them remain at the observation and follow-up stage. Persistent pulmonary nodules (GGO) may be a sign of early lung adenocarcinoma, and data show that 18% of pulmonary GGO with and without solid fraction are pathologically confirmed as lung cancer, respectively. It is well known that surgical resection is still considered to be the preferred treatment for lung cancer, especially for non-small cell lung cancer (NSCLC) with early detection and diagnosis, and surgery is still a possible cure. Several clinical studies have also confirmed that surgical resection, accurate pathological staging and reasonable follow-up individualized treatment can benefit patients in the long term. Special attention should be paid to those who have the following conditions when lung nodules are found: 1. Age above 40 years old, irregular cough, blood in sputum, etc. 2.Smoking age greater than 20 years, smoking volume greater than 20 cigarettes per day and smoking age less than 20 years. 3, immediate family members have a history of lung cancer. 4, work environment harmful toxic substances and long-term chef business, etc. We should take a proactive approach to lung nodules (lung GGO). We should carefully analyze the imaging characteristics of pulmonary GGO under high-resolution CT, determine the proportion of GGO in the nodule according to the consultation opinion of experts in thoracic surgery combined with imaging and medical oncology, decide whether to operate or observe, and make a reasonable judgment on the resection range of surgery combined with the proportion of GGO, the size of the nodule and rapid pathology, etc. For confirmed pulmonary malignant tumor, if the tumor diameter is greater than 1.5 cm, as long as the patient’s cardiopulmonary function permits, lobectomy and precise regional mediastinal lymph node dissection should be performed as much as possible to avoid both blind expansion of surgical indications and surgical scope and not to delay the timing of surgery, which after all has a high five-year survival rate.