Acne is a common inflammatory skin disease characterized by acne, papules, pustules, nodules, cysts and scarring. In the past, the age of acne was high for those who were developing through adolescence, but with the change in lifestyle and environment the age of acne groups has expanded to around 15-45 years old with significant acne symptoms. The usual treatments include oral medications, topical medications, fruit acid peels, and phototherapy (including ultraviolet light, photodynamic therapy, intense pulsed light, dye lasers, fractional lasers, etc.) The main side effects are pain, erythema, edema, and the risk of residual hyperpigmentation. In recent years, microneedling and hydropigmentation have been gradually applied to the clinical treatment of acne and have achieved better results. Microneedling is the use of micro-needles to stimulate the skin to create a large number of microscopic tubes to introduce the hard substances needed by the skin into the skin. Hydrafacial injection is to inject the specified amount of drugs into the skin to the best absorption location directly involved in cell metabolism and inflammation elimination. The skin is induced to repair damaged tissues to achieve bactericidal and anti-inflammatory effects. One is better for epidermal repair and the other is better for deep replenishment. Therefore, this time we will “water light needle” and “micro-needle therapy” combined application, group comparison treatment, to see if we can achieve the effect of one plus one than two. I. Experimental subjects A total of 60 cases of facial acne admitted to our hospital were selected. The cases were randomly divided into treatment group, control group 1 and control group 2. There were 20 cases in the treatment group: 12 males and 8 females, aged 17-38 years old, with an average age of 27.5 years old. Control group 1 20 cases: 12 males and 8 females, age 16-37 years, mean age 26 years. Control 2 group 20 cases: 12 males and 8 females, age 15-36 years, mean age 25.5 years. Exclusion: ① systemic diseases and those with other inflammatory skin diseases in combination. ②Pregnant or lactating women. ③Patients with alcoholism, drug addiction, and mental illness. ④Patients with relevant treatment and skin care in the last three months that affect the determination of results. ⑤ Have severe skin allergies. ⑥Those who have not undergone regular treatment as required and cannot judge the efficacy of the treatment. Second, the choice of medical instruments Water light injector, LED light wave treatment instrument, roller micro-needle, oil control and acne skin care products and hyaluronic acid repair mask. After cleansing, take 5 photos of the patient’s face in the same environment, at the same angle and the same brightness, respectively on the front, left and right 45 degree side, and left and right 90 degree side. If necessary, add the top-down position and local close-up photos. The skin detector was used to monitor the pores, red zone, purple matter, texture and ultraviolet spots of the skin from the left side position, frontal position and right side position respectively, and the test data and photos were recorded and archived. IV. Treatment process Treatment group: combined treatment with hydrophobic micro-needling, 1 month interval, 3 times as a course of treatment. Control 1 group: hydraluminescence combined with oil control acne skin care products, time interval of 1 month, 3 times as a course. Control group 2: roller micro-needling combined with oil control acne skin care products, 1 month interval, 3 times as a course of treatment. Post-operative repair and care were the same for both the treatment and control groups. Hydrafacial injection treatment was specifically: nutrients were injected sequentially in the order of jaw – cheek – temple – around the eye – forehead – nose. The injection can be repeated once for heavier acne. Physiological saline gauze is wiped off the skin surface. Rolling micro-needle, starting from the jaw, slowly rolling over the cheeks, around the eyes, temples and nose in order, and applying the topical solution first. Then localized fast, evenly, different angles, depth evenly sequential rolling 3-5 times. Around the eyes, the strength is reduced, the depth is shallow, and the number of times is 2-3 times. Apply the prepared solution and massage gently until the drug is absorbed. Clean the eye area and jawline with sterile dry gauze. Immediately apply the mechanical hyaluronic acid repair mask and give LED red light for 10 minutes at the same time. Promote pinhole closure and reddening repair, shorten the recovery period and reduce side effects. Precautions: No water within 24 hours after surgery, put on three medical masks, and clean the skin with sterile gauze dipped in mask water before putting on the mask. After that, 1-2 medical masks will be applied every day for one week. For the first three days, wounds repair spray 3-5 times a day. For one week, abstain from spicy food, seafood, smoking and alcohol. For the first three days, the wound repair spray is applied daily for one week. Avoid strenuous exercise and high temperature sauna. During the treatment period, do a good job of hydration, repair and sun protection. After one month, follow up for the next treatment on time. V. Treatment results 1. Clinical efficacy After three months of continuous treatment, the clinician will evaluate the efficacy by combining with the skin test. There are 5 levels: 0 for no improvement, 1 for 1%-24% improvement, 2 for 25%-49% improvement, 3 for 50%-74% improvement, and 4 for 75%-100% improvement. Improvement of grade 3 and above was considered as effective treatment, and the total effective rate was counted. Follow-up visits by phone, weibo or at the hospital were asked whether there were side effects such as excitation of inflammation, skin allergy and pigmentation after each treatment, and the incidence of side effects was recorded. Control group 1 and control group 2 were evaluated and compared according to the same method. II. Satisfaction of candidates All candidates were self-assessed before treatment, after each treatment and after three months of treatment at follow-up visits, and were graded into five levels according to their self-satisfaction: grade A was unsatisfactory; grade B was somewhat satisfactory; grade C was satisfactory; grade D was very satisfactory; and grade E was very satisfactory. The total satisfaction rate was counted with grade C or above as treatment satisfaction. 2. Comparison of results All 60 patients completed 3 treatments as required. The number of patients who reached grade 3 or above in the treatment group was 20, and the self-assessment satisfaction rate was 100% with grade C and above. The number of patients in the control 1 group who achieved grade 3 or above was 19, with an efficiency rate of 95%, one case of self-assessment satisfaction grade B, and 19 cases of grade C and above. In the control 2 group, 18 cases reached grade 3 and above, 2 cases were invalid, and the efficiency rate was 90%. There were 2 cases of self-assessment satisfaction level B and 18 cases of level C and above. Conclusion: Compared with the use of “hydraluminescence” or “microneedling” alone, “hydraluminescence” + “microneedling “The clinicians recognized the combined therapy and the patients were satisfied with the results. (No side effects occurred during treatment in the treatment level control group.) Tips: Previous treatments for acne have included oral medications, topical medications, fruit acid peels, and phototherapy (including ultraviolet light, photodynamic therapy, intense pulsed light, such as dye lasers, fractional lasers, etc.), with major side effects such as pain, erythema, edema, and the risk of residual hyperpigmentation. Hydrafluorescence injections use negative pressure technology to lift the skin and deliver the nutrients or drugs needed by the skin to the skin at the required level in a fixed amount and at a fixed level. The injected dose and injection frequency can be adjusted on the LED display, which is precise and easy to control. In addition, the needle is released from the syringe pressure before it comes out, so there is no loss of nutrients. Microneedling, on the other hand, breaks through the epidermal barrier through extremely tiny orifices (<0.2mm), allowing for a higher rate of drug absorption and penetration than topical drugs, and microneedle rolling can stimulate the skin's self-healing ability, activate cell proliferation, induce the skin's own nutrient and collagen growth, and repair damaged tissue. Therefore, the combination of the two, mastering the depth, density, and concentration of drugs can be stimulated from the inside out, nourishing, anti-inflammatory, sterilization, and promote keratin repair, skin inflammation and metabolic rate are significantly improved, and do not leave surface traces, do not destroy the integrity of the skin structure, safe, reliable, and effective. In this paper, 20 patients in the treatment group were treated with the combination of "hydraluminescence" and "microneedle therapy", and their acne significantly subsided and their closed acne significantly decreased, with good clinical results and no side effects.