Blisters from fire cupping are usually caused by leaving the cupping jar for too long or by too much negative pressure inside the jar, and usually recover in 3-5 days. Blisters from fire cupping are commonly found on the back, ribs, waist and buttocks, and are usually caused by a longer retention time. If blisters appear, they are not large and do not require special treatment, and can recover on their own. However, patients need to avoid scratching and local disinfection to avoid infection. If the blisters are too large to be absorbed on their own, a sterilized needle can be used to puncture the root of the blisters, squeeze out the blister fluid, apply antibiotic ointment and cover with sterile gauze to prevent secondary infection. During the clinical treatment, it should be noted that the cupping time should not be too long, 10-20 minutes is appropriate. If the patient’s skin texture is delicate, the cupping time should be about 5 minutes to avoid blistering for a long time.