Persistent worsening of wheezing in a 72-year-old patient with left ventricular failure relieved by drug therapy

(Disclaimer: This article is for general science purposes only. To protect patient privacy, relevant information in the following content has been processed.) Abstract: Left ventricular failure is a common clinical disease with dyspnea as the main manifestation. The patient in this case was male, 72 years old, and suffered from this disease, manifesting as nocturnal unprovoked wheezing and inability to lie down. After coming to our hospital, he was given diuretic, cardiotonic, vasodilator, and anticoagulant drugs, and the patient’s suffocated wheezing was significantly relieved after 1 week, and his condition was stable. Basic information】Male, 72 years old 【Disease type】Left ventricular failure 【Visiting hospital】The First Affiliated Hospital of Xi’an Jiaotong University 【Visiting time】May 2022 【Treatment plan】Intravenous injection (poppy bases hydrochloride injection, sodium nitroprusside for injection) + oral medication (furosemide tablets, metoprolol succinate extended-release tablets, digoxin tablets, rivaroxaban tablets, warfarin sodium tablets) 【Treatment cycle】Inpatient treatment for 1 week, review after 1 month The patient’s symptoms disappeared and her condition stabilized. The patient was clear, shortness of breath, sweating, unable to lie down, no chest pain, no fever, no cough or sputum, and her symptoms improved slightly after taking quick-acting heart pills outside the hospital. The patient was admitted to the hospital after an emergency chest CT and intravenous administration of poppy alkaloids hydrochloride, and the result of B-type natriuretic peptide precursor was 2429.0 pg/L. Combined with the patient’s symptoms, the patient was initially diagnosed with left ventricular failure. Since the onset, the patient had clear consciousness, shortness of breath, normal urine and unresolved stool. After admission, the patient was given oxygen and cardiac monitoring, and changes in his condition were closely observed. After that, diuretic, cardiotonic, vasodilator and anticoagulant drugs were given to the patient and his family. The patient was given oral diuretic furosemide tablets to increase urinary output and intravenous vasodilator sodium nitroprusside for injection to dilate blood vessels and reduce the burden on the heart. The beta-blocker metoprolol succinate extended-release tablets were used to inhibit the detrimental effect of sympathetic nerves on left ventricular failure, and digoxin tablets were used to enhance myocardial contractility. Rivaroxaban tablets and warfarin sodium tablets were also administered to prevent the formation of thrombus. The patient’s symptoms were relieved after 1 week of medication and discharge could be arranged. III. Treatment effect The patient’s wheezing and suffocation worsened before admission to the hospital, and he could not lie down. After 1 week of treatment with diuretic, cardiotonic, vasodilator and anticoagulant drugs, the patient complained that his wheezing was significantly relieved, and he could rest flat after daily activities without any reduction of symptoms. The repeat B-type natriuretic peptide precursor result was 404.0 pg/L, and the result fell back to the normal range. The patient was discharged from the hospital for convalescence and continued to take furosemide tablets, digoxin tablets, metoprolol succinate extended-release tablets, and warfarin sodium tablets, and was reviewed in 1 month, with prompt medical consultation if there was any discomfort. IV. Precautions After the patient’s condition was stabilized, I was also very happy. In order to have a better recovery after discharge, we should pay attention to the following points in life: 1. After discharge, you should take the drugs on time and according to the dosage, and your family should play a supervisory role to remind you to avoid missing or taking more. 2, diet should be light and easy to digest, avoid the intake of high salt, high fat, high sugar food, so as not to lead to fluid retention, increasing the load on the heart. 3.If your body allows, exercise appropriately. It is recommended to choose low-intensity exercises such as walking and tai chi. 4.After taking medical history, we learned that the patient has a history of smoking, so it is recommended to quit smoking early. V. Personal insight Left ventricular failure is mainly due to the decrease of myocardial contraction leading to the decrease of cardiac blood displacement function, due to the anatomical structure, it will cause pulmonary circulation stasis, and then appear abnormal respiratory symptoms, including unprovoked dyspnea, exertional dyspnea, sitting breathing, nocturnal paroxysmal dyspnea, etc.. In this case, the patient’s main manifestation was unprovoked dyspnea and inability to lie down, and the symptoms were relieved after medication.