Stone bone disease is also known as marble bone, primary brittle osteosclerosis, sclerosing proliferative bone disease and chalk-like bone. It is a rare disorder of bone development. It was first discovered by Albers-Schonberg (1904) and is also known as Albers-schonberg disease. The disease is characterized by the persistence of calcified cartilage, which causes extensive osteosclerosis and, in severe cases, the closure of the greater marrow cavity, resulting in severe anemia. The disease is often familial, with the majority of cases being recessive. It was first reported in 1904 by the German radiologist Albers-Schonberg, who named it “marble bone disease”, and in 1926 Karshnor named it sarcopenia, a rare congenital disorder with a generalized abnormality of bone structure development, with the skull as the site of predilection. It is characterized by increased bone density, bone deformity and involvement of the skull base. The X-ray manifestations of stone bone disease are as follows: 1. Basic X-ray manifestations: widespread uniformity, increased bone density and sclerosis, thickening and blurring of bone trabeculae, cortical thickening, narrowing of the medullary cavity, and even disappearance. There were three cases of stone bone disease in our hospital, due to the occurrence of fracture, want to perform locking intramedullary pin fixation, due to the disappearance of the medullary cavity, bone sclerosis, change to plate or power condylar plate fixation, bone density increase has obvious uniform symmetry, to the extremities, ribs and pelvis more obvious. 2, bone in bone: mainly seen in the metacarpophalangeal, metatarsophalangeal joints and ribs, etc., bone in bone shows a relatively obvious border of dense bone island. 3, sandwich vertebrae also known as sandwich cake sign: its formation is due to the upper and lower cartilage plate of the vertebral body is rich in blood vessels, in the case of insufficient calcium absorption, the part of the excessive deposition of bone-like material. Osteoid has a significant inhibitory effect on osteoclasts, and the lack of this type of bone in the middle of the vertebral body, so the osteoclasts erode, forming the vertebral upper and lower high density and low density in the middle, shaped like a sandwich. 4, the iliac wing of the annual cycle-like changes. The ray-permeable zone is a more normal bone area, while the dense zone has a large number of non-functional osteoclasts. 5, the skull vault skull base are thickened and sclerotic. Bone hyperplasia at the skull base is the most obvious.