Malignant tumors are still one of the world’s most difficult problems, and despite the introduction of various treatments and drugs, most patients are still incurable and develop advanced stages. Physical pain often leads to mental problems. For more than ten years, we have been devoted to improve the quality of life of tumor patients and actively carry out pharmacological treatment for pain, depression and other tumor complications, but the results are not very satisfactory. Many patients still live in pain, tension, anxiety, fear, and even anger, and the mental disorders add to the experience of physical pain. Patients and medical staff, patients and families, and families and hospitals are also often in a state of fire and brimstone. Zhao Wei, Department of Oncology, Guang’anmen Hospital, Chinese Academy of Traditional Chinese Medicine, along with our department’s long-term in-depth study or medical work in the United States, Malaysia, Hong Kong and other countries and regions, we are surprised to find that most of the local patients have a very calm and open-minded attitude, and their quality of life is significantly higher than that of Chinese patients with the same condition, and this improvement in quality of life is not related to their economic status. The reason for this is that in addition to the stability of the local society and the relatively good social security, the religious beliefs of the local residents are a very important reason. In real life, people seldom think about life and death and the passage of time. But once a malignant tumor is diagnosed, these issues immediately come to the forefront. The attachment to real life, the fear of death and suffering, and the uncertainty of the future make patients spiritually lonely, unsupported and helpless. Modern science and medicine tend to focus on the treatment of disease and neglect psychological and spiritual support for patients. Religion, on the other hand, addresses the issues of life, death, and the return of the soul. Religion, as “the sigh of oppressed beings, the feelings of a heartless world,” inevitably brings comfort to a painful life, relieves people’s uneasy emotions (fear, anxiety and dependence), and enables individuals with finite lives to receive or experience some kind of “ultimate care”. One important branch of modern psychology, the psychology of religion, plays an important role in describing and explaining the human psyche and is able to intervene in it and improve its mental health. Religious help is available in hospices and care hospitals in many countries. Numerous research studies have shown that moderate religious psychology is beneficial for tumor patients.1 Religious psychology helps to understand the process of illness, life and death and eliminate fears Among the mainstream religions in today’s society, all have their own explanations for life and death. Buddhism believes that birth, old age, sickness and death are natural processes, and that death is just the beginning of another reincarnation, and that the purpose of practice is to get rid of reincarnation and enter the realm of beauty and light. Christianity believes that there is a beautiful, everlasting heaven outside of the human world, and that the purpose of spiritual practice is to enter heaven after death. All these statements paint a beautiful picture of the soul’s return, a bright future, so that people can reduce or eliminate their fear of the future. People with devout religious beliefs will look at illness and death from a different mindset and not shy away from these topics. By approaching the misfortunes they face from a faith perspective and adjusting their outlook on life and values, they become more at peace and less fearful of illness. When facing death, the attitude is positive and open, and they leave with peace and dignity.2 Religious psychology contributes to positive emotions and a sense of self-happiness People often find that religious experiences can elicit positive emotions and a sense of well-being. These positive emotions can reduce one’s tension and improve one’s quality of life. At the same time, religious experience also leads to altruistic attitudes in people who they see more than others in working for social progress, social problems, or the poor and needy, have more fun with life, are willing to contribute to society, and want to help others. Converts may have been in a state of guilt and depression before conversion, and may have been plagued by illness and suffering, but they feel much better after conversion. The main consequence is a stronger sense of meaning and purpose in life and increased control over their lives. The teachings of a religion are also an important aspect in promoting a greater sense of well-being among its religious people. Religious groups, in general, have strict requirements for alcoholism, crime, marriage, etc. These requirements though said to limit the freedom of the congregation are more conducive to their physical and mental health. In religious communities, some positions like priests are similar to counselors who listen to the confessions and sins of the congregation and forgive their sins on behalf of God. Such activities also play an important role in the mental health of the congregation.3 The communal behavior of religion helps patients to integrate into society.4 Religion also has the greatest psychological impact on people through its communal activities. People are social and need human interaction. Religion provides such an opportunity and place to bring together people with similar ideas and personalities and to promote interpersonal interaction among believers through religious activities, to meet friends, to get recognition, to help others and receive help from others, to improve self-confidence and self-esteem, to clarify the purpose and meaning of their lives, to eliminate loneliness, and to reintegrate into society. However, religious psychology and religious beliefs should be moderate and must be clearly distinguished from foolish superstition and cult heresy. I have seen patients who believe too much in the power of a certain religion and refuse to take medication, which leads to misunderstanding and suffering. Some patients also have superstitious beliefs in fairies and ghosts, and are busy exorcising ghosts and inviting gods after falling ill, resulting in both financial and human losses. Therefore, the heart disease can be adjusted by religion, but the body disease still needs scientific methods of treatment, the two coordinate with each other in order to achieve good results.