Bladder tumor breaking through the plasma membrane layer without metastasis means that the bladder tumor has invaded beyond the plasma membrane layer, but no distant metastasis has occurred.
According to TNM staging of bladder cancer, T1 stage means that the bladder invades the subepithelial connective tissue, T2 stage means that the tumor invades the muscularis propria, T3 stage means that the tumor invades the peripheral tissues of the bladder, and T4 stage means that the tumor invades any of the following organs: prostate gland, uterus, vagina, pelvis, and abdominal wall.M0 means no distant metastasis, and M1 means having distant metastasis.
Bladder tumor breaks through the plasma membrane layer without metastasis is considered as T3~T4 stage, M0. If there is a bladder tumor, it is recommended to actively consult in regular hospitals, you can consult a professional physician to take appropriate treatment plan.