”Holiday heart syndrome” refers to a type of syndrome characterized by arrhythmia after excessive alcohol consumption during holidays. What is the main way to prevent holiday heart syndrome? The first and foremost treatment principle is to quit drinking, which must be done completely to prevent the recurrence of the above-mentioned symptoms from further deteriorating and forming serious arrhythmias or causing the occurrence of heart failure. The second is to give intravenous fluids to promote the timely excretion of alcohol to reduce the damage to the heart. The third is to monitor the electrocardiogram of a few patients with malignant arrhythmias such as atrial flutter or atrial fibrillation, and to administer the necessary antiarrhythmic drugs. In general, after the above treatment, especially within 6-12 hours after the cessation of alcohol consumption, the arrhythmia signs disappear and the heartbeat rhythm and frequency return to normal, so the prognosis is good. In conclusion, the key to preventing “holiday heart syndrome” is to actively stop or reduce alcohol consumption, especially during the holidays to be able to control themselves, less alcohol is appropriate.