Nerve block: It is a nerve block that blocks nerve conduction by injecting drugs directly into or near the endings of nerve trunks, plexuses, brain nerves or spinal nerve roots, sympathetic ganglia and other nerve tissues. Nerve block therapy is used to relieve pain, improve blood circulation and treat painful diseases. It is also known as procaine closure therapy, which is injecting procaine into a local pain point or vein in the body to block the transmission of abnormal stimuli to the brain, thus changing the metabolism of the lesion and accelerating the healing of the disease. The term nerve block has been used worldwide for nearly a century and is still being applied with scientific and normative validity. However, there are still many patients and doctors who refer to “nerve block” or “injection therapy” as “closure”. The term “closure” was created in China in the 1950s, and it was difficult to understand the correct terminology abroad because of the difficulty in exchanging academic information with foreign countries, so it was called habitual for a long time. In fact, the origin of the word “closed” is not found in the English, Russian and Japanese pain literature. This shows that they are two completely unrelated concepts and two very different treatments, and it is not appropriate for a regular doctor to use the informal term “closure. Many people think that the “closed” bones will become brittle, probably because they think that the drug contains hormones, which will lead to osteoporosis, but in fact the little hormone we use in pain treatment is insignificant. As the pain business continues to evolve, the misconception that “nerve blocks” are mistaken for “closures” and even refusal to receive treatment will certainly be clarified!