Can ulcerative colitis be cured? This question is the main concern of most patients. The general principle of treatment for this disease is to induce and maintain remission and improve the quality of life. The disease is classified by WHO as a difficult disease in the world due to its recurrent attacks, long course and difficulty to cure. Ulcerative colitis has a chronic course, and conventional therapeutic drugs are salicylic acid preparations and steroidal corticosteroids are the classical drugs for the treatment of this disease, mainly including 5-aminosalicylates, such as salazosulfapyridine and mesalazine, which are mainly used for the treatment of induction and maintenance of remission in patients with mild to moderate activity, and for distal and rectal lesions of ulcerative colitis, enemas or suppositories are the main drugs used for local administration can increase drug concentrations at the lesion site and reduce systemic drug side effects. Hormones are effective in inducing remission of ulcerative colitis and are mainly used in cases where 5-aminosalicylic acid therapy is ineffective, and in severe cases intravenous systemic hormone therapy is required. In actual clinical practice, in order to achieve better efficacy, reduce abdominal pain, diarrhea, anal swelling, mucopurulent stools and many extra-intestinal symptoms, promote the healing of intestinal mucosal ulcers and reduce patients’ emotional tension, clinical treatment can be combined with Chinese and Western medicines. Chinese medicine follows the guiding principle of dialectical treatment, which can significantly improve the symptoms of diarrhea, abdominal discomfort, shortness of breath and other symptoms of patients according to the characteristics of each patient’s symptoms.