Scientists have known for a long time that inflammation is closely related to cancer, for example, patients with gastric ulcers are prone to stomach cancer and patients with colitis have up to 40% risk of colon cancer. However, it has been a mystery how inflammation of the organ actually triggers cancer. Recently, scientists have discovered through animal testing that the active NF-κB protein in the colon epithelium is responsible for the cancerous development of colitis. The results were published in a recent issue of the American journal Cell. To reduce the occurrence of colon cancer, the first step should be to cure colitis promptly and thoroughly. In China, colitis is often referred to as “ulcerative colitis”, and the lesions are mainly ulcers, mostly involving the sigmoid and descending colon of the rectum, and expanding proximally in a “backwards” pattern, which can spread to the entire colon. The inflammation is mainly located in the mucosal layer, but can also be deeply involved. The acute phase is easily congested, edematous and brittle, and bleeds easily when touched, often with dense and small ulcers. The mucosal surface may be covered with mucopurulent blood. In the subacute phase, the mucosal inflammation is slightly less severe, with granulomatous proliferation, fibrous scarring and epithelial regeneration during repair. In the chronic stage the mucosa is more atrophic, mucosal scarring, narrowing of the intestinal lumen, and formation of pseudo-polyps. Late stage is prone to carcinogenesis. The main symptoms include diarrhea, pus and blood stools, abdominal pain and urgency. Sometimes the stool is constipated and cannot be passed within several days. The course of the disease is long, the severity of the disease varies, and is often accompanied by symptoms such as wasting and weakness, and many recurrent attacks. Causes The causes of the disease are related to autoimmune factors and genetic factors, while the triggering factors are infection by intestinal bacteria and other pathogenic microorganisms and psychological factors. Mental stimulation, exertion, eating disorders, and secondary infections are often triggers for attacks. Because the early symptoms of colitis are insidious and the diarrhea caused by it is easily confused with diarrhea caused by other causes, it is often overlooked by patients. Among clinically diagnosed colon cancer patients, 60% of them had suffered from colitis. They either treat colitis-induced diarrhea as general diarrhea, take some medicine casually and ignore it as long as they don’t have diarrhea; or they don’t take it seriously even after being diagnosed, which makes the disease recur and eventually leads to bad consequences. The actual fact is that you can find a lot of people who are not able to get a good deal on a lot of things. The patient is also reminded that the treatment of colitis should not simply be aimed at anti-inflammatory and sterilization, but should also regulate the balance of intestinal flora, repair the damaged intestinal mucosa, and improve the overall function of the intestinal tract. Keeping a good mood and cooperating with treatment at the same time can control colitis in order to keep away from colon cancer. Warm reminder: If you have anorectal problems, you can call our hotline for free consultation. The actual fact is that you can’t delay the disease for a long time, some anal diseases will seriously harm the patient’s health if you don’t treat them for a long time, and it’s easy to induce other anal diseases all in one, which will seriously harm the patient’s health and affect the patient’s normal life, therefore, if you find yourself suffering from some anal diseases in your life, you must timely The actual symptoms of the disease must be promptly checked and treated at a professional anorectal hospital.