Acute urticaria in children can cause respiratory distress and anaphylactic shock in severe cases, which can be life-threatening. Acute urticaria is a skin rash-like lesion caused by drugs, food or other factors, with a rapid onset and severe itchiness, which usually disappears spontaneously within a few hours. In severe cases, it may cause respiratory distress and anaphylactic shock because of edema in the laryngeal area, and shortness of breath, dyspnea, and asphyxia, as well as fainting, loss of consciousness, and sudden collapse due to extensive capillary dilatation and a drop in blood pressure, which can seriously jeopardize the life of the child. If children have the above symptoms or are diagnosed with acute urticaria, it is recommended that they go to the hospital in a timely manner and receive standardized treatment under medical guidance in order to reduce the adverse effects.