What is an individualized protocol for liver cancer intervention?

Selection of interventional therapy suitable for patients Different interventional therapy plans should be formulated according to the type and size of liver tumor, the presence or absence of portal vein thrombus, the degree of cirrhosis, the status of liver function, age and systemic condition of each patient. For example, for elderly patients with hepatocellular carcinoma or those with severe cirrhosis, simple chemotherapeutic embolization should be given by ultra-selective cannulation in the feeding artery of the tumor; for patients with dense iodine-oil deposition in the large part of the hepatocellular carcinoma lesion and iodine-oil defects in a small part of the edge of the lesion as found in the post-interventional follow-up, anhydrous alcohol can be injected directly under the guide of B-ultrasound. The interval of interventional therapy depends on the follow-up. Usually, the interval between interventions is 50 days-3 months each time, in principle, at least 3 weeks from the patient’s recovery from the last intervention. If there is dense iodine oil deposition in the liver tumor lesion on imaging, tumor tissue necrosis and no new lesion or no new progress, intervention is not allowed for the time being. Protecting patients’ liver function Most of the primary liver cancers are tumors occurring on the basis of cirrhosis after hepatitis, and their liver function is often abnormal or at critical value. Although interventional therapy has better curative effect on liver tumors, it also inevitably damages the liver function of patients. Using microcatheter super-selective cannulation technique, chemotherapy and embolization can be successfully given from the target vessel, which can effectively control the tumor and protect the liver function of the patient. For the number of tumors less than three, the microcatheter should be used to superselectively insert the feeder arterial branches around the periphery of each tumor, respectively; for the number of tumors more than three, the microcatheter should be inserted into the right or left hepatic artery, and the gallbladder artery should be avoided. The collateral feeder arteries of the tumor should also be searched and dealt with.