Risk factors for coronary heart disease in hyperlipidemic and hypercholesterolemic populations Serum total cholesterol levels are directly proportional to the morbidity and mortality of coronary heart disease. Serum cholesterol concentration is associated with causing coronary heart disease. The relative risk of coronary heart disease in hypercholesterolemic patients is 5. Cholesterol binds to proteins in the body to form lipoproteins, of which low-density lipoprotein cholesterol (LDL-C) is the main source of cholesterol in atherosclerotic plaques, and high-density lipoprotein cholesterol (HDL-C) is negatively correlated with the occurrence of coronary heart disease. Therefore, recently people pay much attention to the role of HDL-C and serum total cholesterol (TC) ratio, TC/HDL-C as a predictor of coronary heart disease, when its ratio is greater than 4.4, the risk of coronary heart disease incidence is significantly higher. Hong Hao, Department of Cardiothoracic Surgery, Wuhan Union Medical College Hospital The earlier the age at which the serum cholesterol level rises, the greater the chance of coronary heart disease in the future. Coronary heart disease risk factors of overweight and obesity cardiology hospital physician pointed out that over the standard weight of obesity is coronary heart disease susceptibility factors. Obesity can make blood pressure and serum cholesterol rise. Overseas research shows that: 10% increase in body weight, blood pressure increased by an average of 0.86kPa (6.5mmHg), serum cholesterol increased by an average of 18.5mg%. 35 to 44 years old male body weight increased by 10%, the risk of coronary heart disease increased by 38%, body weight increased by 20%, the risk of coronary heart disease increased by 86%. Coronary heart disease risk factors of diabetes coronary heart disease is the most common complication of diabetic patients, hypertensive patients with diabetes, the chance of developing coronary heart disease is twice as high as hypertensive patients without diabetes.