Hives to stop itching can take oral antihistamines, such as oral loratadine, cetirizine and so on. Urticaria is a generalized or localized skin eruption with itching caused by contact with allergic substances. Acute spontaneous urticaria preferred sedative effect of the second generation of H₁ receptor antagonist treatment, commonly used drugs are loratadine, cetirizine, ibastine, fexofenadine, etc.; topical drugs can be chosen from glycerine lotion, phenylephrine cream. Specific medication should be used in accordance with the doctor’s instructions. At the same time, we should actively search for allergens, and avoid the suspected allergens in order to avoid the recurrence of the disease. If the disease is serious, accompanied by shock, laryngeal edema and respiratory distress, it is necessary to go to the emergency department in time to avoid life-threatening.