Vulvovaginitis in young girls is a common disease in pediatric gynecology. For various reasons, clinical treatment is very difficult and the disease is persistent. It is not only physically and mentally harmful to the child, but also makes parents anxious. The disease occurs in young girls between the ages of 3 and 8 years old, mostly in summer, and lasts from 1 to 6 months, or up to 2 years or more. Children often feel itchy and painful vulva, usually without frequent, urgent and painful urination, and without systemic symptoms. Physical examination reveals a flushed and congested vulvar-vaginal opening with or without abnormal discharge, which is often accompanied by an odor. Since the internal and external genitalia of young girls are not yet mature, estrogen is lacking, the vaginal mucosa is thin and wrinkle-free, and the vagina is low in acidity due to the lack of intracellular glycogen, the natural defense ability is low, so it is easy to be attacked by various pathogens and irritants and infections can occur. If you don’t pay attention to keep your vulva clean, especially if you don’t wipe your anus properly after each bowel movement, you will easily contaminate your vulva with stool and infection will occur unknowingly. Vulvovaginitis in young girls is usually caused by vaginitis first, followed by inflammatory secretions that stimulate the vulva of young girls, which lacks the protection of pubic hair. Most of them are conditional pathogens, such as Escherichia coli, Streptococcus, Staphylococcus and Aspergillus, and a few are gonococcal, mycoplasma and fungal infections. What’s more, vulvovaginitis in young girls is often combined with two or more pathogens. There are many contraindications in choosing sensitive antibacterial drugs for children, such as the possible effects of quinolones on bone development and the ototoxicity and nephrotoxicity of aminoglycosides. Another problem is that because the secretions for bacterial culture cannot be taken directly from the vagina of young girls, and the secretions from the vaginal opening are easily contaminated by surface pathogens, the reference significance of bacterial culture results is limited, which also increases the difficulty of clinical treatment to a certain extent. 4, external washing treatment is difficult for vaginitis in adult women, taking appropriate medication to rinse the vagina to make the germs and secretions fully discharged is crucial for the cure of the disease. However, it is difficult to do this for vulvovaginitis in young girls. In addition, the douche tubes that accompany the commonly used gynecological drugs on the market today are for adults, while small douche tubes suitable for young girls are not available. 5. For other causes of treatment, it is also necessary to consider the combination of vulvovaginitis in young girls with other diseases. In one case, it was reported in the literature that a soybean accidentally entered the vagina while a child was playing. Due to the presence of a foreign body in the vagina, the vulvovaginitis remained untreated for a long time and was only cured after the foreign body was found and removed by rectal palpation. In another report, a child was infected with pinworms, and at night the anal sphincter relaxed, so the pinworms crawled out of the anus and entered the vagina, resulting in a long-lasting vulvovaginitis, which was cured only after deworming treatment. The parents should do the following to prevent vulvovaginitis in their young daughters 1, keep the vulva clean parents help baby girls before bathing, to wash hands thoroughly. After a young girl has a bowel movement, she should wipe her anus along the direction away from the vagina to prevent the bowel from contaminating the vaginal opening. It is true that it is more convenient for children to wear crotch pants for urination and defecation, especially in rural areas where it is still common for children to wear crotch pants, but it is not hygienic for baby girls to play on the floor in crotch pants and it is also easy for foreign objects to enter the vagina. Parents should teach their children simple protection knowledge. Parents should teach their young girls to be hygienic, wash their hands regularly, don’t play with their vulva and don’t sit on the floor. Parents should take their children to a regular hospital once they find that they are scratching or rubbing their vulva, or that their vulva is red and has discharge.