Breast eczema is an eczema-like disease that occurs on the breast area, including the nipple and areola, mostly in breastfeeding women, with acute and subacute eczema as the main clinical manifestation. Breast eczema generally starts as a dark red rash on the breast area, with the development of the disease process on the rapid emergence of scattered papules, papules, accompanied by obvious itching, at this time need to use topical drugs with heat dissipation, anti-itch, anti-inflammatory effect, and the dosage form is easy to lotion, cream, such as furnace glycolate lotion, a variety of weak glucocorticoid ointment. If the disease is more serious, local papules have occurred erosion, exudation, it is necessary to use boric acid lotion and other solutions of wet compress treatment, after the rash exudation is reduced and then change to oil with soothing, astringent effect to continue treatment until the exudation disappears. In addition, some patients may develop bacterial infections secondary to localized fissures and other skin injuries, which may require topical antibiotic treatment in conjunction with the above treatment. It is important to note that systemic antihistamines are generally not recommended for breast eczema in patients with breastfeeding needs. First, most antihistamines can be excreted through breast milk, and some of them lack a safety basis for neonatal application; second, antihistamines have a certain inhibitory effect on glandular secretion while competitively binding to histamine receptors, which can easily lead to a decrease in milk secretion. Therefore, since oral antihistamines can negatively affect normal breastfeeding in terms of both safety and secretion, standardized and effective topical medication should be given when breast eczema occurs in order to control the condition and promote healing as soon as possible.