Can cirrhosis of the liver cause diabetes?

Hepatogenic diabetes can occur in cirrhosis because the liver is an important organ for the metabolism of the three major nutrients. A decrease in liver function in cirrhosis can lead to a disruption in the liver’s metabolic processes of glycogen synthesis, reserve, and catabolism, resulting in elevated blood glucose. Another cause of hepatogenic diabetes is also related to hormone inactivation disorders caused by liver disease, which can lead to an increase in glucagon and therefore an increase in blood glucose. Patients with cirrhosis can also have reduced glucose tolerance and are also prone to diabetes. The difference between hepatogenic diabetes and ordinary diabetes is that it is mainly postprandial hyperglycemia, while fasting blood sugar can be normal. However, patients with cirrhosis are not recommended to use glucose-lowering drugs, but mainly to use insulin to lower blood sugar and blood sugar is not recommended to be too low.