Cold urticaria, also known as cold contact urticaria, can be categorized into two types, one is related to genetic predisposition and the other is mainly caused by exposure to cold wind and cold air. Cold urticaria is considered to be genetically related if it occurs in infants and young children. It is an autosomal dominant disorder, which is relatively rare, starts in infancy and can last for a lifetime. Adult onset of the disease is usually acquired, due to exposure to cold air, cold water or other cold objects, resulting in the activation and degranulation of a variety of inflammatory cells in the body, such as mast cells, and the release of inflammatory activity of chemicals, such as histamine, pentazocine, etc., which causes vasodilatation, increased permeability, resulting in the appearance of hives on the skin and mucous membranes and other parts of the body. Usually, you should avoid eating cold drinks, ice-cream and other cold foods, avoid contact with cold water, pay attention to warmth, mild symptoms can be oral antihistamines, such as cetirizine, loratadine, and vitamin C tablets for treatment; symptoms should be obvious in time to consult a doctor, according to the performance of individual compliance with individualized treatment.