Infertility is diagnosed when a couple lives together with a normal sexual life and has not been pregnant without contraception for 1 year ( 6 months if the woman is over 35 years old). It is then time to seek the help of a doctor at a qualified and regular hospital. It is important to avoid blind tests, which may lead to wasted money or even delay the best time to conceive. What items should be checked for the first time? Generally speaking, you should start with the simplest and least invasive tests. The main tests include: 1. Semen examination of the male partner: semen examination is the most basic examination item for infertile couples, which is fast and non-invasive. The semen should be collected by the husband within 2-7 days after intercourse. Semen should be collected by masturbation method or in vitro ejaculation method, not by condom. The semen examination can provide information on the number, morphology and motility of the male partner’s sperm and malformation rate, which can help determine or rule out most male causes. If 2 semen tests are suggestive of azoospermia, a testicular biopsy should be done by a male physician, and if there is mature sperm, IVF can be done. If there is no sperm, donor insemination or IVF is needed. 2. Female partner’s ovulation test: The first test for the female partner should be done on the morning of the 3rd-5th day of menstruation on an empty stomach to test the basal sex hormones and a vaginal ultrasound to understand the number of basal follicles. The next step is to determine whether the woman is ovulating or not. The methods used to determine ovulation include ultrasound monitoring, basal body temperature measurement and ovulation test strips. If possible, ultrasound monitoring of follicle development is recommended, starting from day 10 of the menstrual cycle until after ovulation. These methods are non-invasive and easy to perform. 3. Tubal imaging: Usually performed on an outpatient basis, 3-7 days after menstruation (note the need to abstain from sex), it can help to understand the condition of the uterus and fallopian tubes of the woman. However, repeated tubal imaging and lysis are not recommended because repeated lysis and imaging not only do not help in treatment and diagnosis, but can cause infection and endometrial damage. If the cause of infertility is still not determined by these tests, further tests may be needed. At this point, you will need to consult with your primary care physician to determine if the next tests are needed based on your condition (as not all patients need them). The common ones include laparoscopy and hysteroscopy, and depending on your condition, you can have just one test or a combined hysteroscopy at the same time. 1.Laparoscopy. It is possible to understand pelvic adhesions and perform tubal patency test at the same time, but requires anesthesia and hospitalization. 2.Hysteroscopy. It can understand the endometrial condition and whether there are deformities and adhesions in the uterine cavity. Simple hysteroscopy can be done on an outpatient basis, and intravenous anesthesia is available for patients who are sensitive to pain. Complex hysteroscopic procedures require hospitalization and anesthesia. It is especially important to point out that if some patients are determined to be able to conceive only through IVF after a series of examinations, they should stop seeking medical help from all over the place and consider IVF technology directly to avoid both detours, time-consuming and costly, and delaying the best time and way to conceive.