Generally, there is progressive wasting in a short period of time, with weight loss before and after the measured weight value control, and there are obvious clothes become loose, the belt becomes loose, shoes become larger as well as subcutaneous fat reduction, muscle thinness, skin laxity caused by the cheeks obviously sunken, which aspects of the examination should be made in the hospital visit? 1, genetic and family history Somatic wasting often has a family history without pathological manifestations. There is often a family history of hyperthyroidism, diabetes mellitus, and pheochromocytoma (multiple endocrine adenoma syndrome). Certain malignant tumors have a family history of development. 2, economic status and dietary habits, such as whether calorie intake is adequate, whether there is sufficient protein, whether partial or omnivorous diet, whether raw fish, shrimp and crab, raw vegetables, raw beef and mutton habits, such as raw water red rhombus, plum raising, lotus root and other aquatic plants can cause gingerbread disease, parasitic in the small intestine, causing diarrhea, digestive disorders, malnutrition; raw food or eating uncooked fish, shrimp, crab, etc. can be infected with Toxoplasma gondii. Raw or uncooked fish, shrimp, crab, etc. can be infected with bilharzia, raw crab or tobacco can be infected with lung bilharzia; raw or uncooked beef, pork can be infected with tapeworm disease; eating vegetables, fruits and vegetables with parasitic eggs, unclean water can be infected with cysticercosis, encapsulated cysticercosis, ascariasis, etc., all can cause wasting. 3, place of origin, occupation There are more water fields in the south of China, farmers or fishermen repeatedly contacted with the epidemic water contaminated with schistosomal tails, infected with schistosomiasis; pastoral contact with cattle and sheep, animal sheds may be infected with cysticercosis, cysticercosis; hookworm disease and ascariasis are more common in rural areas, serious infection can have wasting. 4.Other medical history Ask about the history of sexual contact, male homosexual history, whether there is a history of drug use or use of narcotic drugs, because the use of unclean or shared needles, etc. can spread AIDS.