Acetaminophen is available in oral solution, tablets, and suppositories. Suppositories are often administered rectally and usually take effect about 30 minutes to an hour after administration. Acetaminophen is a common antipyretic and analgesic used in the clinic, mainly for fever caused by the common cold and influenza, but also for the relief of mild to moderate pain, such as headache, arthralgia, muscular pain, neuralgia, and toothache. In general, the drug can work 30 minutes to 1 hour after rectal administration, will reach the peak of blood concentration in about 2 hours, and continue to exert the effect of the drug for about 4 hours or so. Although acetaminophen is currently more commonly used antipyretic drugs, but need to pay attention to the use of medication, in the antipyretic should not be used for more than 3 days of continuous use, for pain relief should not be used for more than 5 days of continuous use, it is recommended that the patient to follow the doctor’s instructions for the use of medication.