Many patients often ask about the significance of a positive HSVIgG serological test for genital herpes, and the explanation on the Internet is not particularly clear, so here is an answer. First of all: IgG is an antibody, no infection with herpes virus (HSV) will not produce HSVIgG antibodies, so a positive HSVIgG indicates a previous infection with HSV, once the herpes virus (HSV) is infected it is not possible to say that there is any way to remove the virus, which means that HSV infection cannot be cured. Since IgG antibody positivity can also last for years, it is right to check HSVIgG antibody to see if you have been infected with HSV, and since HSV has a subclinical infection, HSVIgG antibody positivity is not wrong to diagnose herpes virus infection (not necessarily genital herpes) even if there are no symptoms, and genital herpes can be diagnosed if there is a history of recurrent episodes in the genital area. It is a bit complicated to summarize in one sentence: HSVIgG positive can be said to have been infected with HSV, which can be diagnosed as HSV infection, but not genital herpes, and should be combined with clinical manifestations to see if the infection is in the genital area; second: the current confusion is that many people overemphasize the diagnostic significance of HSV2IgG positive for genital herpes, and overemphasize the incurability of HSV, giving patients with very high mental and economic stress; Third: HSV type 1 has a high infection rate in the population, and most people can be detected as HSV1IgG positive, because most genital herpes are HSV2 infections, so many patients are afraid of HSV2IgG positive; Fourth: Whether type 1 or type 2 HSVIgG antibodies have a certain protective effect on the body, HSVIgG positivity can persist for many years without change. Therefore, a positive HSVIgG antibody cannot be used as a criterion to determine whether genital herpes has recurred or whether treatment is needed! It is totally wrong to treat HSVIgG when it is positive and especially to use expensive treatments to try to turn IgG treatment negative; Fifth: It is currently believed that there is no exact relationship between genital herpes and cancer, etc. HSV cannot be completely eradicated and there are no expensive drugs or so-called high-tech instrumental means or prescriptions to remove HSV; Sixth: The human immune system is very complex and there is no existing Seventh: HSV is only transmitted by contact, and the most contagious time is when the herpes is red and itchy before it comes out and the first few days of the herpes. Eighth: HSVIgM only appears briefly after the first HSV infection, disappears quickly, and is not positive when it recurs, and is only relevant for diagnosing the first HSV infection.