Generalized weakness is the main clinical manifestation of novel coronavirus infection, but there are many causes of generalized weakness, such as hypothyroidism, diabetes, hyperthyroidism, colds, etc. It can also be caused by fatigue or poor sleep. Of course, for those at high risk, i.e. those who have recently travelled to infected areas and come into contact with patients who may have been infected, it is important to pay attention to the presence of novel coronavirus infection if they are still within the incubation period and to have early blood tests, chest CT and especially nucleic acid tests of respiratory secretions.