Recently, Professor Wang, Director of Biliary and Pancreatic Surgery of Shanghai Hospital, led his team to complete the first da Vinci robotic pancreaticoduodenectomy in our hospital. Pancreaticoduodenectomy is considered to be the most difficult, challenging and traumatic surgery in general surgery due to the large number of organs removed, complex anatomy and postoperative complications. Even traditional open surgery is often difficult and can only be performed by extremely experienced general surgeons, with patients having incisions up to 750px or more. Because of the deep anatomical location of the pancreas, the richness of surrounding blood vessels, the difficulty of resection and the high precision of suturing, it has been the bottleneck of minimally invasive surgery, and the minimally invasive surgery of pancreaticoduodenectomy at home and abroad has been in a slow development and exploration stage, and only a few centers can carry out laparoscopic pancreaticoduodenectomy at present. In recent year, the Department of Biliary and Pancreatic Surgery, under the leadership of Professor Wang Jian, has ventured into the forbidden area of surgery and continuously challenged the difficult surgery, and has successfully carried out laparoscopic pancreaticoduodenectomy. However, laparoscopic reconstruction of the anastomosis of the pancreas and intestine, bile and intestine has always been a difficult part of laparoscopic pancreaticoduodenectomy, which requires a long learning curve and a lot of energy and time for the medical staff at the beginning stage, which is a physical and mental and willful challenge for the medical staff. With the advent of the da Vinci Surgical Robot System, many of the problems of laparoscopic technology have been solved. The robotic arm of the robot system can rotate 360 degrees, making suturing precise and convenient, while providing a clearer surgical field and a more accurate imaging system, making the surgery more precise and delicate, with less intraoperative bleeding, and ultimately achieving rapid postoperative recovery. The patient, a 65-year-old male, was admitted to the hospital for one month due to abdominal pain, and was diagnosed as duodenal papillary tumor by CT. The patient was diagnosed with duodenal papillary tumor through CT. The tumor has no obvious symptoms in the early stage and has an insidious onset. The operation was carried out smoothly with the skillful operation of Director Wang Jian and the cooperation of his assistant. Through fine freeing and precise dissection, the operation was performed with almost no bleeding, and the first pancreaticoduodenal resection of duodenal papilla tumor under the robot was completed, which opened the “robot era” of biliary and pancreatic surgery in Renji Hospital. One day after the operation, the patient was transferred out of the care unit and was in stable condition. At present, the patient is recovering well and has been discharged from the hospital. Since the establishment of the Biliary and Pancreatic Surgery Department one year ago, under the leadership of Prof. Wang, the chief of the department, the department has applied the concept of “minimally invasive precision surgery” to complex hepatobiliary and pancreatic surgeries and carried out all kinds of minimally invasive surgeries and techniques to cure patients while minimizing their trauma and providing guarantee for their rapid recovery. At present, we have carried out laparoscopic pancreaticoduodenectomy, laparoscopic pancreatic body caudal resection, laparoscopic choledochal cystectomy with bile-intestinal anastomosis, laparoscopic hepatic segment resection, laparoscopic biliary tract exploration, single-port laparoscopic cholecystectomy and other difficult surgeries. With the first robot-assisted pancreaticoduodenectomy in our hospital that was successful, it marks that biliary and pancreatic surgery has fully entered the minimally invasive era, and the concept of precision surgery with minimally invasive as the core will bring gospel to more and more patients through the comprehensive combination of robotics and laparoscopic technology.