Simple tympanic membrane perforation is mainly caused by a partial decrease in the function of the tympanic membrane to conduct sound. The symptoms can usually be significantly improved after tympanic membrane healing and tympanic membrane repair, and the treatment varies depending on the cause of the disease. For tympanic membrane perforation caused by trauma, attention needs to be paid to the cleanliness and dryness of the external ear canal. If there is no obvious infection, there is no need to use antibiotics. It is important to prevent colds and to avoid blowing the nose too often. For larger or non-healing perforations, tympanic membrane repair is an option. Acute otitis media resulting in tympanic membrane perforation can also heal basically after controlling the infection and keeping the external ear canal clean and dry. For perforations caused by chronic suppurative otitis media, CT and MRI examinations of the ear should be completed to clarify the extent and severity of the lesion. Simple tympanic membrane perforation can be treated by repair surgery, while other types require different surgical procedures depending on the examination results.