Cold Circulation Microwave Knife is an emerging means of tumor treatment, which is an improved treatment modality of the traditional percutaneous puncture microwave coagulation therapy for tumors (PMCT), and belongs to minimally invasive interventional therapy. Guided by ultrasound or CT, the microwave knife is accurately positioned and directly punctured to the tumor site. Polar molecules in the tissue move at high speed under the action of microwave field, friction with each other generates heat, which rapidly warms up in the tumor, and when the temperature rises to about 60 degrees Celsius, the protein of the tumor cells degenerate and coagulate, resulting in irreversible necrosis and inhibiting the proliferation of the tumor cells, and meanwhile, the impact on the surrounding normal tissues is very small, with low side effects. Low side effects. Cold cycle microwave knife has the advantages of image guidance, accurate positioning; minimally invasive, small damage to patients, fast recovery; direct ablation of tumor cells, precise efficacy; high safety, etc. It is mainly used in the clinical treatment of liver cancer and other solid liver tumors. Xiangya Hospital of Central South University Hepatobiliary and Intestinal Surgery Research Center of the Ministry of Health is the unit that introduced microwave knife earlier in China, and has achieved good therapeutic effect in clinical treatment.