Resistance is the body’s immune mechanism, which is used to express the body’s ability to resist the invasion of external pathogenic microorganisms. A variety of reasons such as overwork, stress, lack of nutrients, taking drugs, etc. can cause the body resistance to decline. Different causes should be dealt with in different ways. 1, proper rest: overwork will lead to lower metabolism and overall functioning of the body, affecting the efficiency of the body’s immune system to carry out immune surveillance and immune defense, leading to a decline in resistance. Ensure adequate rest can maintain the vitality of the body, so that the immune system is always in a highly efficient state; 2, relaxation: stress caused by anxiety, tension and other emotions will affect the immune system to play a role in reducing resistance. Maintaining a good mood will help stabilize the functions of the body, which will help improve resistance; 3, supplemental nutrients: the lack of some nutrients, such as protein, inorganic salts, vitamins, will lead to lower resistance. You can eat more meat, eggs, milk, fresh fruits and vegetables to supplement nutrients, enhance resistance; 4, moderate exercise: moderate exercise can make the body a variety of functions to be strengthened, so that the immune system is more efficient, resistance will also be enhanced. In addition, the treatment of some diseases take drugs and immunosuppressants, etc. will act on the immune system to reduce immunity, according to the situation of the use of alternative drugs or stop drugs.