The reason for the disappearance of the tumor from the advanced stage of lung cancer may be the result of aggressive treatment. Lung cancer is a common malignant tumor of the respiratory system caused by smoking, environment, heredity and other factors. When the disease develops to the advanced stage, there is often no chance of surgical resection, and it is mostly treated by non-surgical therapies such as radiotherapy, chemotherapy, targeted therapy and so on. Therefore, when patients actively cooperate with doctors in treatment, the phenomenon of tumor disappearance can occur. After active treatment, the five-year survival rate of patients with advanced lung cancer is about 10%. However, the purpose of treatment in this period is to prolong the survival period and improve the quality of life of patients. After surgery, patients should follow the doctor’s instructions for regular review and quit smoking in daily life, which can reduce the recurrence rate of the disease.