Why do we need radiotherapy before surgery to treat supraglottic lung cancer? Prof. Jian You: Early symptoms of suprasellar lung cancer are not obvious, and the local invasion of the tumor is often very serious by the time it is found. If the invasion is extensive, radiotherapy, chemotherapy or simultaneous radiotherapy can be done before surgery, with three main purposes: first, to make the tumor shrink; second, to kill the potential cancer cells in the infiltrated tissues around the tumor; and third, to reduce the hemotransportation (i.e., transportation and circulation of blood) in the infiltrated areas around the tumor, so as to reduce intraoperative blood seepage. It is also worth noting that not all patients undergo radiotherapy prior to surgery. Some patients do not require chemotherapy if their preoperative evaluation suggests that they can proceed directly to radical surgery. What is the survival rate of preoperative radiotherapy + surgical resection? Prof. Jian You: According to foreign literature, patients with upper lung sulcus cancer who can undergo radical surgery have a 5-year survival rate of 40%-59%, which is much higher compared with ordinary lung cancer.