Lymph node hyperplasia, or lymph node reactive hyperplasia, is an enlargement of lymph nodes due to reactive proliferation of lymphocytes and histiocytes in the lymph nodes caused by various injuries and stimuli. It can be seen in diseases such as necroproliferative lymphadenopathy, serum sickness and serum sickness-like reaction. If the symptoms of lymph node hyperplasia are mild, there is no pressure pain, no adhesions, and no other symptoms, treatment may be unnecessary for the time being, and only close observation of the changes is needed. However, if abnormal changes such as rapid and fast growth occur, you should seek medical attention promptly. For the treatment of lymph node hyperplasia, a comprehensive judgment should be made according to the location, causative factors and nature of lymph node hyperplasia before deciding on further treatment. First of all, the cause of the disease should be clarified, and then the treatment should be directed at the primary cause. For lymph node enlargement caused by acute and chronic inflammation due to viral and bacterial infections, antibiotic treatment can be carried out according to the type of infecting bacteria, and the commonly used drugs include penicillin, streptomycin, erythromycin, etc. For primary tumors such as lymphoma, various types of acute and chronic leukemia and plasma cell tumors, as well as enlarged lymph nodes caused by metastasis of malignant tumors such as lung cancer, liver cancer, breast cancer and nasopharyngeal cancer, treatment with surgery or radiotherapy is required in conjunction with the condition. Lymph nodes are the most sensitive “alarms” for human diseases. Once abnormalities occur, it indicates that there is a problem in a certain part of the body, so we must not take it lightly, but observe it carefully and intervene early.