Patient: Description (time of onset, main symptoms, hospital visited, etc.): Mandibular defect I had a titanium plate repair, but the appearance was not good. Is the technology of tissue-engineered bone mature now? Is it possible to use tissue-engineered bone to repair a partial defect of the mandible? Chai Gang, Department of Plastic Surgery, Shanghai Ninth People’s Hospital: Generally, most of the mandibular defects are after tumor surgery, and the tissues are more atrophied after radiotherapy. Surgery time: generally 6 months later can be. Surgical methods: 1, the beginning of the use of fibular flap repair, restoration of bone continuity, preferably with full digital design to ensure surgical accuracy and ultimate symmetry; 2, in addition, a variety of plastic surgery techniques including fat injection, scar correction and other methods to achieve the reconstruction of facial shape, restore the quality of life requirements.