In most cases, patients with Parkinson’s disease will welcome the start-up about one month after the brain pacemaker surgery. Excessive optimism, or excessive pessimism and negativity, or too many family members around at the time of start-up can cause psychological stress to the patient and adversely affect the start-up outcome. Patients with Parkinson’s disease may have differences in response time to stimuli in patients with similar conditions due to differences in patient fitness. Patients with Parkinson’s disease may require several programmed sessions to optimize stimulation parameters and make adjustments to medications after start-up. The overall goal is to alleviate symptoms and prevent adverse reactions, and in principle, the least amount of stimulation intensity and the least amount of medication should be used to obtain the greatest improvement in clinical symptoms. Some patients may have the question, why the effect is so good on the day of opening, how come it is not as good as that day after going home? So, what are the causes of the above problems? 1, the “excellent” state when the machine is turned on, mainly after the rapid relief of muscle tension, a long-lost comfort, contrast is obvious. It is like the first sip of water for a person who is thirsty; 2. The reason that the postoperative period is really much better, but not as good as the start-up period, is that the excellent state of the start-up period makes the patient believe that it is perfectly possible to expect to return to the state before the disease. So after going home, the discomfort that slowly emerged was mainly due to the discrepancy between the actual situation and the expectation, always believing that that extremely good state would be maintained all the time. At the early stage of starting the machine, while feeling the good status of the pacemaker, some people who used to be especially afraid of the side effects of drugs would not follow the doctor’s advice to reduce the medication, but secretly take less or no medication; 4, after starting the machine, the muscle tone decreases, and the usually stiff limbs and joints become much more flexible, but the lack of muscle strength that existed before is obviously manifested, and they feel “weak, unable to walk”. I can’t walk”. The good start-up condition can be stabilized by effective methods. Deep brain stimulation (DBS) therapy is the most advanced method to control and improve the symptoms of Parkinson’s disease. However, for patients in the middle and late stages of the disease, they should not put all their expectations on adjusting their pacemakers and recovering better or similar to normal people, but they also need timely rehabilitation exercises (mainly muscle strength improvement and body balance exercise) and retraining of their life skills (starting from self-care) after starting the machine. The post-operative period can be used to regain a good state of health. It is a good choice to take advantage of the good condition after surgery, to regain the hobbies lost due to illness, and to engage in beneficial physical and mental activities.