Lyme disease is a global zoonotic disease caused by the bacterium Borrelia burgdorferi and spread by the bite of bedbug-like ticks (commonly known as grass crawlers or grass lice). It was first discovered in 1975 in the town of Lyme, Connecticut, USA. Since 1986, many places in China (especially mountainous areas, forest areas and pastoral areas) have also emerged one after another the prevalence of this disease, with the increase in recent years to the mountainous areas, forest areas, pastoral areas and natural epidemic areas and other places of tourism, the incidence of this disease has increased significantly, the region has a tendency to expand, such as once the disease and misdiagnosis and mistreatment, the consequences will be very serious, so it can not fail to draw due attention to the tourism season this year has This year, the tourist season is approaching, so I would like to give you a warning. People and susceptible animals such as rats, rabbits, dogs, wolves, pigs, chickens and birds can all be infected and become ill from the bite of a tick with bacteria. The chance of people becoming infected depends largely on the length and frequency of actual contact with ticks in areas of high prevalence versus natural epidemiological origin. The prevalence of the disease is then related to the density of local ticks and the climate, with peak tick activity occurring during the wetter and warmer months of April to May and August to September each year. When a tick bites the above-mentioned animal with bacteria or disease, Burkholderia cepacia will be inhaled into the tick body. These small insects often rest on small grasses and treetops, waiting for an opportunity to crawl first to the legs, hands, feet and neck of pedestrians, and often prefer to stay in the warmer parts of the body such as the groin and armpits. Spirochetes are injected into the human body through tick bites and are dispersed throughout the body with blood and lymphatic fluid. Spirochetes can survive for long periods of time in human tissues, blood, cerebrospinal fluid, and joint fluids, and if improperly and untimely treated, will lead to constant relapses into remission and into chronic inflammatory pathology that will not heal for long periods of time. In the early stage, spirochetes mostly travel to the skin and cause chronic wandering erythema. The erythema is mostly found in the lower abdomen, inner thighs and armpits, accompanied by mild painful itching and burning sensation, which usually heals spontaneously after 2 months but can recur elsewhere. Some patients may have varying degrees of headache, fever, malaise and enlarged lymph nodes. If the heart is damaged weeks to months after onset, symptoms such as myocarditis, pericarditis, myocardial hypertrophy, atrioventricular block, and left ventricular insufficiency may develop, often lasting days to weeks, and often recurring. If the nervous system is damaged, symptoms such as aseptic meningoencephalitis, neuritis (facial neuritis is the most common), and myelitis may occur repeatedly and enter a chronic phase after several months and have varying degrees of neurological sequelae. If the bones and joints are damaged weeks to years after the onset of the disease, recurrent episodes of sudden monoarthritis or wandering polyarthritis similar to rheumatoid arthritis may occur, with the large joints, such as the knee, being the most commonly damaged and prone to joint deformation and disability. Severe damage to the heart and brain can lead to death. Popular knowledge of disease prevention is an important part of the prevention and control of the disease, especially when traveling into mountainous, forested and pastoral areas, and their poultry and livestock farms during the peak season of tick activity, you should especially strengthen personal measures against tick bites. For example, wear long pants, long-sleeved shirts, long elastic socks and gloves, and tuck the cuffs of your pants and cuffs tightly into your socks and gloves; tuck the hem of your top into your pants and tie them tightly (you can also wear a windbreaker or jacket instead), wear a wide-brimmed hat, and wear a tight-necked top and tie your collar tightly. When returning to your residence, take off your clothes, hat, pants and socks, and gloves outdoors to remove any ticks attached to your clothing for safety. In the unlikely event that Lyme disease is detected, you should go to the hospital immediately, as early treatment with antibiotics, such as penicillin, can achieve good results.