What should I do if my tumor markers are elevated? After surgery or inoperable radiotherapy, tumor patients often have elevated tumor markers, but comprehensive examination does not reveal obvious signs of metastasis. Facing this situation, some patients choose to continue chemotherapy, but more patients and their families feel confused by the toxic side effects of chemotherapy. Long-term clinical practice shows that Chinese medicine has a certain role in reducing the elevation of many tumor markers in lung cancer, gastric cancer, breast cancer, gynecological tumors and so on. The following is a typical case of our clinical treatment using TCM alone. Post-operative gastric cancer, poor hematopoietic function after chemotherapy, intermittent elevation of multiple tumor markers (TM), among which the value and number of elevated CA199 were the highest The patient was male, 74 years old, the patient developed abdominal distension and black stool in February 2003, checked fecal occult blood (++++) in Beijing Haidian Hospital, upper gastrointestinal barium meal and gastroscopy found: gastric body – huge occupancy. Postoperative pathology: ulcerated hypofractionated adenocarcinoma, invading the whole layer, no cancer invasion in the upper and lower margins, cancer metastasis in the lymph nodes of the small curvature (16/17), cancer metastasis in the lymph nodes of the large curvature (2/11), no cancer infiltration in the greater omentum. From April 2003 to January 2004, the patient was treated with 6 cycles of chemotherapy with “L-OHP + 5-FU + CF”, during which no abnormal tumor markers were observed. The patient refused further chemotherapy and requested to be treated with traditional Chinese medicine alone. The first CA199 increase: 2005.03.30, CA199: 42.1 U/L (reference value: 0-37). The patient was in good general condition at the first consultation, with occasional acid reflux and dysphagia, cough with a small amount of white mucous sputum, acceptable appetite, acceptable sleep, regulated bowel movements, red tongue with little coating and thin pulse. The diagnosis is that the liver and stomach are not in harmony and phlegm and dampness are contained within. After 10 days of treatment with herbal compound injection, CA199 was rechecked on April 1, 2005: 32.12 U/ml, which returned to normal. CA199 and CEA were both increased: 2007.7.19, carcinoembryonic antigen (CEA): 6.30 ng/ml (0-5), CA199: 40.81 U/L. The patient had abdominal distension, belching, coughing up a small amount of white sputum, bowel movements were possible, urinary frequency, urgency and nocturia were frequent, 2-3 times/night. The tongue is red with a watery coating and the pulse is stringent. After 22 days of treatment with traditional Chinese medicine, abdominal distension and belching improved significantly, coughing and sore throat. 2007.8.13: CEA: 5.68ng/ml, CA199: 35.20U/ml. 9g of Radix Platycodon grandiflorus and 10g of Radix chrysanthemum were added and the coughing and sore throat were relieved after 7 doses. 2010.8.31: rechecked CEA: 2.61ng/ml, back to normal. CA199, CYFRA21-1, SCC were increased: 2010.06.07: CA199:41.03U/ml, cytokeratin 19 fragment 21-1 (CYFRA21-1): 7.97ng/ml (reference value: 0-3.3), squamous epithelial carcinoma antigen (SCC): 3.1ng/dl (reference value: 0-1.5). The patient had abdominal distension, acid reflux, heartburn, pain in the liver area, weakness, shortness of breath, cough, coughing up white mucous sputum, red tongue, thin white coating, and slippery pulse. The diagnosis was: liver depression, spleen deficiency and deficiency of lung qi; the treatment was to de-stress the liver and strengthen the spleen with qi: the formula was: prolotherapy with addition and subtraction, 14 doses were taken, together with herbal compound anti-cancer injection. The patient complained of abdominal distension, acid reflux and heartburn, and the tumor markers were rechecked: CEA: 6.27ng/ml, CYFRA21-1: 4.01ng/ml, SCC: 1.9ng/dl, CA199: 39.34U/ml. CA199, CYFRA21-1, SCC all decreased, but still higher than normal: 2010.11.24, CYFRA21-1: 3.48ng/ml, SCC: 2.7ng/ml, CA199: 39.62U/ml. The patient had nausea, acid reflux, aggravated after eating, occasional liver pain, weakness, shortness of breath, sleep, and bowel movement. The prescription was based on the evidence that liver qi is unstable and lung qi is deficient. After taking 14 doses, 2010.12.17: Tumor markers (TM) were normalized after rechecking.