We often encounter patients with crestal medullary injuries in clinical practice, some due to car accidents, some due to falls while working, and some due to bruises and cuts. Crestal medullary injury often leads to paralysis directly due to fracture and joint dislocation compressing the crestal medulla, but there is another kind of crestal medullary injury where there is no fracture and no joint dislocation, and the injury may also lead to paralysis, and a check of MRI only indicates crestal medullary injury. Many doctors or family members are at their wits’ end when faced with quadriplegia after a crestal medullary injury, and even if the family gives the patient full authority to the doctor, the doctor is often helpless in the face of such a patient, thus leaving these patients in bed for a long time, unable to take care of themselves, incontinent, and losing confidence in life, which leads to thoughts such as lightness of life. Is there really nothing that can be done for these patients with crestal marrow injury? Let’s look at a case first. The patient, a 65-year-old male, fell to the ground from a height while working and suffered a cervical crestal medullary injury, which led to immediate tetraplegia and immobility. The magnetic resonance suggests cervical 3-4 level crestal medullary injury and cervical spinal stenosis For the treatment of crestal medullary injury probably most doctors only know to use hormones, so they did use hormones, but the efficacy was very poor, and the patient was still quadriplegic after one week of treatment, then he was transferred to the functional neurosurgery department of Xi’an Red Cross Hospital, and at the time of admission the patient had level 1 muscle strength in both upper limbs and level 2 muscle strength in both lower limbs. After 20 days of treatment, the patient was able to stand up, walk on the ground and hold chopsticks to eat. Crestal medullary injury is indeed very beatable and can easily lead to limb paralysis, urinary and fecal incontinence and other symptoms, which seriously affects the patient’s life treatment, but with early and effective treatment, most of the crestal function can be improved and restored without leading to permanent paralysis. However, if there is fracture dislocation compressing the crestal medulla, it is necessary to perform surgery to decompress and release the compression as soon as possible. 1. In the acute stage, treat the fracture and combined injuries first, actively rescue the life and maintain stable vital signs. In the acute stage, we can use hormone shock therapy for a short period of time, combined with nerve-nourishing drugs, etc. At the same time, we should take into account the prevention of deep vein thrombosis (wearing long elastic stockings, prophylactic use of low-molecular heparin, etc.), prevention of decubitus ulcers to enhance care, prevention of pulmonary infection, prevention of urinary retention and constipation (manually assisted massage of the abdomen to help gastrointestinal movement). After the edema period, electrical and magnetic stimulation can be performed as soon as possible to promote neurological recovery.