Wandering pain mostly occurs in rheumatoid arthritis and rheumatoid arthritis. Doctors call the pain type in which the joints of the whole body rotate pain as “wandering pain”. In contrast, pain that is limited to localized pain in the joints is simple arthritis. The scope of pain in simple arthritis is relatively small. Its main signal of disease pain is from the inflammation in the joint cavity. What are the examination items for rheumatoid arthritis? 1, X-ray examination: generally more check the hand and foot joints, sometimes the foot joint performance is not much, but the X-ray has seen bone destruction. Early stage patients X-ray is generally negative except for soft tissue swelling and joint exudate. After a few weeks or months, osteoporosis near the joint is seen. Later, destruction of the soft surfaces of the joint, narrowing of the joint space, irregularity of the joint surface, and increased bone destruction in the late stage are seen as joint subluxation until bony ankylosis. It is mostly seen in lesions older than 2 years. Osteoporosis may be increased by hormone therapy. 2, bursal fluid examination: arthrocentesis fluid is translucent straw yellow fluid, leukocytes (2-7.5) × 109/L, polymorphic nuclei > 50%, negative cell culture, active phase can be seen in the leukocyte plasma containing RF and IgG complement complex inclusion body phagocytes, called rheumatoid cells. RF in joint fluid may be positive. 3, immunological examination: IgG, IgM and IgA are mostly increased, complement is mostly normal, but C3 can be reduced in those with significant vasculitis, and cold globulin can be increased. Anti-nuclear antibody positivity rate is about 15%. Acute phase protein examination: C-reactive protein, mucin and fibrinogen may be increased, and blood sedimentation may be increased, but they are not specific.