High and low blood pressure requires control of causative factors, change of poor lifestyle, standardized medication, and exclusion of secondary hypertension. Standardized home self-measurement of blood pressure and ambulatory blood pressure monitoring can help detect blood pressure fluctuations as early as possible. Commonly used interventions are as follows: 1. Control the causative factors: Under the guidance of a physician, make effective therapeutic lifestyle changes, quit smoking and limit alcohol, eat regularly, control blood sugar to meet the standard, maintain emotional stability, avoid overwork, continuous tension, excessive stress, staying up late, and if you cannot regulate your emotions by yourself, please visit a psychiatrist promptly. Avoid heat stroke, dehydration, malnutrition and other diseases. Insufficient blood volume can lead to hypotensive shock. Take antihypertensive drugs regularly and quantitatively; use drugs that raise blood pressure carefully, such as glucocorticoids, tricyclic antidepressants, certain diet drugs, recombinant human erythropoietin, cyclosporine, etc. 2, medication standardization: hypertension drugs are usually taken on an empty stomach, when the drug reaches the peak time and the peak blood pressure time is the same, can better control blood pressure. The number of antihypertensive drugs to be taken strictly in accordance with medical advice, regular, quantitative, regular dosing about 1-2 weeks, can play a clear antihypertensive effect, 2-4 weeks of blood concentration stabilization, in order to achieve a smooth antihypertensive effect. It is generally recommended to take long-acting antihypertensive drugs, if the blood pressure changes in a special pattern, can also be long and short-acting with, to achieve the best antihypertensive effect. 3, secondary hypertension: pay attention to the investigation of common secondary hypertension causes, such as renal artery stenosis, pheochromocytoma, etc.. Unstable blood pressure can easily induce acute cardiovascular and cerebrovascular events, such as acute myocardial infarction, cerebral hemorrhage, cerebral infarction, aortic coarct and other critical illnesses. It should be treated actively according to the specific situation.