Why should patients with atrial fibrillation take Warfarin?

  The heart has a small tissue called the sinus node, which is the commander that controls the entire heartbeat, and it regularly and regularly distributes bioelectricity, which reaches the entire heart through the conduction tissue, causing the heart to produce synchronized and coordinated contractions. When atrial fibrillation occurs, the control function of the sinoatrial node is lost, and another bioelectricity is issued by one part of the atria, which is fast and irregular, causing the contraction of the atria to stop and causing the ventricles to have fast irregular beats, up to 100-150 times, or up to 200 times in some cases, and the heart rate is not consistent with the pulse rate at this time.  Because the original rhythm of the atria disappears, it cannot contract regularly, which not only affects the heart function, but also makes it easy to grow thrombus in the atria, and once the thrombus is dislodged, it will cause acute embolism in the peripheral arteries, and the embolism will cause stroke in the brain.  Warfarin is an anticoagulant drug that prevents thrombosis. Warfarin maintains the patient’s international normalized value (INR) at 2.0-3.0 and reduces the incidence of stroke by 68% and the overall mortality rate by 33% in patients with atrial fibrillation. However, the biggest complication of Warfarin is bleeding, so it is necessary to monitor the coagulation function and keep the INR at 2.0-3.0. If you take Warfarin together with herbs such as Salvia, Ginkgo, Ginseng and Licorice, you need to reduce the amount of Warfarin because these herbal ingredients can enhance the anticoagulant effect of Warfarin, while American Ginseng weakens the anticoagulant effect of Warfarin. If you are taking American ginseng, you need to increase the amount of Warfarin as appropriate.