Mastocytosis (also known clinically as breast adenopathy and breast pain) is a benign hyperplastic disease of the ductal epithelium, surrounding connective tissue and lobules of the breast. The disease is common in women aged 25-40 years. It is currently thought to be related to endocrine disorders and psychological factors. A decrease in luteinizing hormone secretion and a relative increase in estrogen are important causes of this disease. Women with infertility, late marriage, few children, age at first birth >35 years old and short breastfeeding are the most common group of women with mastocytosis. Periodic pain and lumps in the breast are the main clinical manifestations of the disease: 1. Breast pain is often swelling or stabbing pain, which can involve one or both breasts, with one side being the most common. The pain is mainly at the breast lump, but can also be radiated to the affected armpit, chest or shoulder back; some are manifested as nipple pain or itching. Breast pain often appears or worsens a few days before menstruation and decreases or disappears after menstruation; pain can also fluctuate with emotional changes. This pain associated with the menstrual cycle and emotional changes is the main feature of the clinical manifestations of mastopathy. Breast lumps can occur unilaterally or bilaterally in the breasts, singly or repeatedly, preferably in the upper outer quadrant of the breast, but also in other quadrants. The shape of the masses may be lumpy, nodular, striated, granular, etc., among which lumpy is the most common. The masses have inconspicuous borders, medium or slightly hard texture, good mobility, no adhesions with surrounding tissues, and often painful to touch. The size of the lump varies from a small one as large as a grain of corn to a large one of 3 to 4 cm, and the size of the lump varies with the menstrual cycle. In addition, a few patients may have nipple overflow, yellow-green, brown or blood-colored, and occasionally colorless plasma. How to prevent and relieve 1, less anger, maintain emotional stability, optimism and cheerfulness; long-term mental depression or intense mental stimulation can easily lead to breast enlargement. 2, change the diet, avoid caffeine-containing beverages, estrogen-containing feed-fed poultry, freshwater aquatic products; eat less fried food, too sweet food and overly stimulating food; eat more vegetables and fruits, eat more coarse grains. 3, life should be regular, work and rest, to maintain a harmonious sex life. Can regulate endocrine disorders, keep the bowels will reduce breast swelling and pain, can play a role in the prevention of mastocytosis. 4, more exercise, to prevent obesity to improve immunity. 5, prohibit the abuse of contraceptives and estrogen-containing beauty products. 6, mastocytosis patients underwear can be appropriate loose, too tight underwear will affect the blood circulation and lymphatic reflux of the mammary glands. 7, the prevention of mastocytosis also pay attention to avoid abortion, medical abortion, maternity after childbirth for breastfeeding, for the benefit of children and themselves.