Principles of antiepileptic drug use: 1. early medication 2. selection of drugs according to seizure type 3. single drug principle, combined medication if necessary 4. principle of individualization of medication dose 5. long-term regular medication 6. regular review 7. addition and reduction of medication norms side effects of major antiepileptic drugs 1. sodium valproate: bone marrow suppression, liver function damage, gastrointestinal reactions such as vomiting and diarrhea, fever rash and other allergic reactions. 2. Bone marrow suppression, liver function damage, fever rash and other allergic reactions, headache, dizziness and fatigue. 3. lamotrigine: rash and even Stevens-johnson syndrome, headache, dizziness and fatigue, drowsiness. 4. topiramate: fatigue, drowsiness, ataxia, abnormal sensation, inattention, food aversion, weight loss. 5. levetiracetam: personality abnormalities, abnormal thinking, hostility, vertigo, fatigue 6. Clonidine: drowsiness, ataxia, nystagmus, increased respiratory secretions, hypotonia, cognitive and behavioral abnormalities.