Rheumatoid arthritis pain is commonly treated with non-steroidal anti-inflammatory drugs, and glucocorticoid therapy can be applied when necessary. Non-steroidal drugs have a rapid onset of action, analgesic effect is better, commonly used drugs including indomethacin, diclofenac, etoricoxib, etc., can play a fever, analgesic, anti-inflammatory effect, but can not control the progression of rheumatic disease. They have side effects on the digestive tract, kidneys and cardiovascular system, and should be used with caution in people with abnormal renal function or a history of peptic ulcer. For patients with severe symptoms or poor results of anti-inflammatory drugs alone, glucocorticoids can be applied, which have powerful anti-inflammatory and immunosuppressive effects and can relieve symptoms, commonly used drugs include prednisone, methylprednisolone, etc., and during the period of taking the drug, it is necessary to closely monitor the occurrence of related adverse reactions. It is recommended that the patient under the guidance of a physician to standardize the use of drugs, can reap better results and reduce the incidence of adverse reactions, do not take the drug on their own, so as not to cause adverse consequences.