Diagnosis and differential diagnosis of hepatic hemangioma

  Hepatic hemangioma is the most common benign tumor of the liver, and the pathological type is mostly cavernous hemangioma. In recent years, the detection rate of asymptomatic patients has increased significantly with the popularity of health checkups and various advances in diagnostic imaging techniques. Because some hepatic hemangiomas may rupture and involve important structures of the liver, they require surgical intervention, but there are few relevant basic and clinical studies and the diagnosis and treatment lack mature and standardized criteria. Currently, the diagnosis of hepatic hemangioma mainly relies on various imaging examinations, and the current status of treatment is the coexistence of various means such as surgery, hepatic artery embolization and radiofrequency ablation. Despite a better understanding of the pathophysiology and natural course of hepatic hemangioma, the determination and selection of treatment indications, timing and modalities are still controversial, and a consensus that has been confirmed by large-scale, multicenter clinical studies and is widely accepted at home and abroad is urgently needed.  Ultrasound is the first choice for clinical screening of hepatic hemangioma because of its low cost, high prevalence, safety and reliability, and good reproducibility, and its typical presentation is a well-defined hypoechoic occupancy with less pronounced posterior echogenic enhancement. MRI has special diagnostic significance for this disease, with uniform low signal on T1-weighted image and clear margins, and obvious high signal on T2-weighted image, which is typical of “light bulb sign”. “light bulb sign”.  Through imaging examination, most of the hepatic hemangiomas can be accurately diagnosed, and a few cases need to be differentiated from hepatocellular carcinoma, focal nodular hyperplasia and hepatic adenoma. According to our national situation, it is necessary to know whether the patient has a background of hepatitis and cirrhosis, and the accuracy of diagnosis can be improved by combining with tumor marker tests such as alpha-fetoprotein and CA19-9. For cases that still cannot be diagnosed clearly, surgical exploration can be carried out prudently, which can achieve both diagnostic and therapeutic purposes.